Cannabinoid Receptor 1
A cannabinoid receptor antagonist, also known simply as a cannabinoid antagonist or as an anticannabinoid, is a type of cannabinoidergic drug that binds to cannabinoid receptors (CBR) and prevents their activation by endocannabinoids. They include antagonists, inverse agonists, and antibodies of CBRs. The discovery of the endocannabinoid system led to the development of CB1 receptor antagonists
Cannabinoid Receptor 2
Cannabinoid receptors are of a class of cell membrane receptors under the G protein-coupled receptor superfamily. Cannabinoid receptors are activated by three major groups of ligands: endocannabinoids, produced by the mammillary body; plant cannabinoids (such as Cannabidiol, produced by the cannabis plant); and synthetic cannabinoids (such as HU-210). All of the endocannabinoids and plant cannabinoids are lipophilic, such as fat soluble compounds
Pinene is a bicyclic monoterpenoid. Akin to its name, pinene has distinctive aromas of pine and fir. There are two structural isomers of pinene found in nature: α-pinene and β-pinene. Both forms are important components of pine resin. α-pinene is the most widely encountered terpenoid in nature. Pinene is found in many other conifers, as well as in non-coniferous plants. It is found mostly in balsamic resin, pine woods and some citrus fruits. The two isomers of pinene constitute the main component of wood turpentine. Pinene is one of the principal monoterpenes that is important physiologically in both plants and animals. It tends to react with other chemicals, forming a variety of other terpenes (like limonene) and other compounds.
Pinene is used in medicine as an anti-inflammatory, expectorant, bronchodilator and local antiseptic. α-pinene is a natural compound isolated from pine needle oil which has shown anti-cancer activityand has been used as an anti-cancer agent in Traditional Chinese Medicine for many years. It is also believed that the effects of THC may be lessened if mixed with pinene.
What Is Pinene?
Pinene, which comes in two different varieties Alfa and Beta-Pinene, is an aromatic compound found in a variety of plants. The compound has a characteristic earthy smell that is similar to what you would expect in a pine forest. Some of the main plants known to have the compound include pine trees, orange peels, rosemary and basil among others.
This compound is also one of the main active compounds found in marijuana plants. In the past a lot of research has been devoted into studying, pinene, one of the most common tarpenes found in nature.
Read on below to find out more about pinene, and its known effects as established by scientific studies.
As previously stated, pinene is an aromatic compound found in a variety of plants. In marijuana, this compound is among the tarpenes identified as fragrant oils produced by the plants. They are primarily used to defend the plant against natural predators. It is however important to note at this point that pinene’s properties extend far beyond the simple aromatic ones mentioned above, as far as humans are concerned. The compound has been found to have a variety of positive benefits on marijuana users as discussed below.
Health Benefits of Pinene
Tarpenes such as pinene have different effects on the marijuana user’s body, just like cannabinoids. These effects usually contribute to the properties of different strains, giving each one its specific identity.
The main pinene effects known to date include helping prevent any short term memory loss associated with the effects of THC, acting as an anti-inflammatory, enhancing alertness and improving airflow to the lungs. As you can see, pinene is effective in reducing the psychoactive effects of THC. This in effect means that marijuana users feel less high after using strains with high pinene concentrations. The most significant health effect of pinene is the ability to decrease the size of cancerous tumors.
How Pinene Works
Pinene is able to achieve the above effects due to its ability to successfully cross the blood brain barrier. In the brain, the compound is able to help enhance memory by acting on neurotransmitters. It is also able to help reduce the psychoactive effects of THC while acting on the brain as well.
Marijuana strains that have a high concentration of pinene usually result in a high characterized by feeling active and alert. These strains are also great for people suffering from asthma.